COVID-19 vaccines may help some cancer patients fight tumors

COVID-19 vaccines may help some cancer patients fight tumors
Health Secretary Robert F. Kennedy Jr. has raised skepticism about mRNA vaccines, cutting $500 million in funding for some uses of the technology. (AP)
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COVID-19 vaccines may help some cancer patients fight tumors

COVID-19 vaccines may help some cancer patients fight tumors
  • A healthy immune system often kills cancer cells before they become a threat

WASHINGTON: The most widely used COVID-19 vaccines may offer a surprise benefit for some cancer patients – revving up their immune systems to help fight tumors.
People with advanced lung or skin cancer who were taking certain immunotherapy drugs lived substantially longer if they also got a Pfizer or Moderna shot within 100 days of starting treatment, according to preliminary research being reported Wednesday in the journal Nature.
And it had nothing to do with virus infections.
Instead, the molecule that powers those specific vaccines, mRNA, appears to help the immune system respond better to the cutting-edge cancer treatment, concluded researchers from MD Anderson Cancer Center in Houston and the University of Florida.
The vaccine “acts like a siren to activate immune cells throughout the body,” said lead researcher Dr. Adam Grippin of MD Anderson. “We’re sensitizing immune-resistant tumors to immune therapy.”
Health Secretary Robert F. Kennedy Jr. has raised skepticism about mRNA vaccines, cutting $500 million in funding for some uses of the technology.
But this research team found its results so promising that it is preparing a more rigorous study to see if mRNA coronavirus vaccines should be paired with cancer drugs called checkpoint inhibitors — an interim step while it designs new mRNA vaccines for use in cancer.
A healthy immune system often kills cancer cells before they become a threat. But some tumors evolve to hide from immune attack. Checkpoint inhibitors remove that cloak. It’s a powerful treatment – when it works. Some people’s immune cells still don’t recognize the tumor.
Messenger RNA, or mRNA, is naturally found in every cell and it contains genetic instructions for our bodies to make proteins. While best known as the Nobel Prize-winning technology behind COVID-19 vaccines, scientists have long been trying to create personalized mRNA “treatment vaccines” that train immune cells to spot unique features of a patient’s tumor.
The new research offers “a very good clue” that maybe an off-the-shelf approach could work, said Dr. Jeff Coller, an mRNA specialist at Johns Hopkins University who wasn’t involved with the work. “What it shows is that mRNA medicines are continuing to surprise us in how beneficial they can be to human health.”
Grippin and his Florida colleagues had been developing personalized mRNA cancer vaccines when they realized that even one created without a specific target appeared to spur similar immune activity against cancer.
Grippin wondered if the already widely available mRNA coronavirus shots might also have some effect, too.
So the team analyzed records of nearly 1,000 advanced cancer patients undergoing checkpoint inhibitor treatment at MD Anderson – comparing those who happened to get a Pfizer or Moderna shot with those who didn’t.
Vaccinated lung cancer patients were nearly twice as likely to be alive three years after beginning cancer treatment as the unvaccinated patients. Among melanoma patients, median survival was significantly longer for vaccinated patients – but exactly how much isn’t clear, as some of that group were still alive when the data was analyzed.
Non-mRNA vaccines such as flu shots didn’t make a difference, he said.


University of Virginia strikes deal to pause Trump administration investigations

University of Virginia strikes deal to pause Trump administration investigations
Updated 6 sec ago

University of Virginia strikes deal to pause Trump administration investigations

University of Virginia strikes deal to pause Trump administration investigations
  • The deal, Mahoney wrote, preserves the university’s academic freedom and doesn’t hurt its attempts to secure federal research funding

WASHINGTON: The University of Virginia has agreed to abide by White House guidance forbidding discrimination in admissions and hiring, becoming the latest in a growing list of campuses striking deals with the Trump administration as the college tries to pause months of scrutiny by the US Justice Department.
The agreement was announced by the Justice Department, which began investigating the admissions and financial aid processes at the Charlottesville campus in April. Federal officials accused Virginia’s president of failing to end diversity, equity and inclusion practices President Donald Trump has labeled as unlawful discrimination.
The mounting pressure prompted James Ryan to announce his resignation as university president in June, saying the stakes were too high for others on campus if he opted to “fight the federal government in order to save my job.”
Unlike some universities’ deals with the Trump administration, the Virginia agreement announced Wednesday does not include a fine or monetary payment, said Paul Mahoney, interim president of the university, in a campus email. Instead, the university agreed to follow the government’s anti-discrimination criteria. Every quarter, the university must provide relevant data showing compliance, personally certified by its president.
The deal, Mahoney wrote, preserves the university’s academic freedom and doesn’t hurt its attempts to secure federal research funding. And the university won’t have external monitoring by the federal government beyond quarterly communications with the Department of Justice.
If Virginia complies, the Justice Department said it would officially end its investigations.
Virginia’s settlement follows other agreements signed by Columbia and Brown universities to end federal investigations and restore access to federal funding. Columbia paid $200 million to the government, and Brown paid $50 million to Rhode Island workforce development organizations.
Some of the Justice Department’s letters squarely took aim at Ryan, accusing him of engaging in “attempts to defy and evade federal anti-discrimination laws and the directives of your board.” Much of the federal scrutiny centered on complaints that Ryan was too slow to implement a March 7 resolution by the university’s governing board demanding the eradication of DEI on campus.
As a public university, the University of Virginia was an outlier in the Trump administration’s effort to reform higher education according to the president’s vision. Previously, the administration had devoted most of its scrutiny to elite private colleges, including Harvard and other Ivy League institutions, accused of tolerating antisemitism.
Since then, the White House has expanded its campaign to other public campuses, including the University of California, Los Angeles, and George Mason University.
The Charlottesville campus became a flashpoint this year after conservative critics accused it of simply renaming its DEI initiatives rather than ending them. The Justice Department expanded the scope of its review several times and announced a separate investigation into alleged antisemitism in May.
Among the most prominent critics was America First Legal, a conservative group created by Trump aide Stephen Miller. In a May letter to federal officials, the group said Virginia had only moved to “rename, repackage, and redeploy the same unlawful infrastructure under a lexicon of euphemisms.”
Similar accusations have embroiled George Mason University, where the governing board came to the defense of the president even as the Education Department cited allegations that he promoted diversity initiatives above credentials in hiring. On Aug. 1, the board unanimously voted to give President Gregory Washington a pay increase of 1.5 percent. The same day, the board approved a resolution forbidding DEI in favor of a “merit-based approach” in campus policies.
The University of Virginia deal with the Justice Department did not include one of the investigations the federal government had launched into the college. The Education Department had included the Charlottesville campus in a March 10 list identifying 60 universities that were under investigation for alleged antisemitism.
A department spokesperson said she could not confirm whether the investigation is still open because the agency’s Office for Civil Rights is furloughed during the government shutdown. She said the agreement does not resolve any department investigations.


US says two dead in strike on alleged drug-smuggling boat in Pacific

US says two dead in strike on alleged drug-smuggling boat in Pacific
Updated 22 October 2025

US says two dead in strike on alleged drug-smuggling boat in Pacific

US says two dead in strike on alleged drug-smuggling boat in Pacific
  • The strike brings the total number to at least eight, leaving at least 34 people dead
  • “There were two narco-terrorists aboard the vessel during the strike, which was conducted in international waters. Both terrorists were killed,” Hegseth said

WASHINGTON: A new US strike on an alleged drug-smuggling boat killed two people, Defense Secretary Pete Hegseth said Wednesday, announcing Washington’s first such attack on a vessel in the Pacific Ocean.
The strike — which Hegseth announced in a post on X that featured a video of a boat being engulfed in flames — brings the total number to at least eight, leaving at least 34 people dead.
“There were two narco-terrorists aboard the vessel during the strike, which was conducted in international waters. Both terrorists were killed and no US forces were harmed in this strike,” Hegseth said of Tuesday’s action in the eastern Pacific.


“Just as Al-Qaeda waged war on our homeland, these cartels are waging war on our border and our people. There will be no refuge or forgiveness — only justice,” he wrote.
President Donald Trump’s administration has said in a notice to Congress that the United States is engaged in “armed conflict” with Latin American drug cartels, describing them as terrorist groups as part of its justification for the strikes.
“The president determined these cartels are non-state armed groups, designated them as terrorist organizations, and determined that their actions constitute an armed attack against the United States,” said the notice from the Pentagon, which also described suspected smugglers as “unlawful combatants.”
But Washington has not released evidence to support its assertion that the targets of its strikes are drug smugglers, and experts say the summary killings are illegal even if they target confirmed narcotics traffickers.

- Regional tensions -

There were survivors of a US strike for the first time last week, but Washington chose to repatriate them rather than put them on trial for their alleged crimes.
Ecuador released one after finding no evidence that he had committed a crime, while authorities in Colombia said the other — who “arrived with brain trauma, sedated, drugged, breathing with a ventilator” — would face prosecution.
The US military campaign — which has seen Washington deploy stealth warplanes and Navy ships as part of what it says are counter-narcotics efforts — has fueled tensions with countries in the region.
This is especially the case with Venezuela, where the buildup of US forces has sparked fears that the ultimate goal is the overthrow of President Nicolas Maduro, whom Washington accuses of heading a drug cartel.
The United States has not specified the origin of all the vessels it has targeted, but has said that some of them came from Venezuela.
Meanwhile, a public feud between Trump and Colombia’s leftist leader Gustavo Petro intensified in recent weeks over the Republican president’s deadly anti-drug campaign.
Trump on Sunday vowed to end all aid to the South American nation — a historically close US partner and the world’s leading cocaine producer — and branded Petro, who has accused the US president of murder, as an “illegal drug dealer.”
But just days later, the Colombian president met with the top US diplomat in his country to discuss counter-narcotics efforts, with Bogota’s foreign ministry saying the two sides “reaffirmed the commitment of both parties to improve drug fighting strategies.”


Man taken into custody after driving his car into security gate outside White House, authorities say

Man taken into custody after driving his car into security gate outside White House, authorities say
Updated 22 October 2025

Man taken into custody after driving his car into security gate outside White House, authorities say

Man taken into custody after driving his car into security gate outside White House, authorities say
  • The man was immediately arrested by officers from the Secret Service’s uniformed division
  • Investigators searched his car and deemed it to be safe

WASHINGTON: A man was taken into custody late Tuesday after driving his car into a security barrier outside the White House, authorities said.
The US Secret Service said the man crashed into the security gate at a White House entrance at 10:37 p.m. on Tuesday.


The man was immediately arrested by officers from the Secret Service’s uniformed division, the agency said.
Investigators searched his car and deemed it to be safe, Secret Service officials said in a statement.
The man, whose name wasn’t immediately released, was taken to a hospital for a mental health evaluation, according to a Secret Service spokesperson.
He is expected to be charged with unlawful entry and destruction of government property, the spokesperson said.


During cold and flu season, the youngest kids really are the germiest

During cold and flu season, the youngest kids really are the germiest
Updated 22 October 2025

During cold and flu season, the youngest kids really are the germiest

During cold and flu season, the youngest kids really are the germiest
  • “Young children can have up to 10 respiratory viruses a year as their immune systems are introduced to different infections for the first time,” said Dr. Goldman, a pediatrician
  • Preventing illness in children at school or at home can be tough, experts acknowledge

BEIRUT: Forget colorful leaves. Any caregiver knows that the real signs of fall are kids with coughs, sneezes and sniffles.
Autumn marks the start of respiratory virus season, when colds, flu and other bugs start circulating — especially among the very young.
A recent study confirmed what many families intuitively know: The littlest students harbor the most germs.
Children in pre-kindergarten and elementary school showed highest rates of virus detection compared with older students and staff, according to research published in the journal Pediatrics.
“Young children can have up to 10 respiratory viruses a year as their immune systems are introduced to different infections for the first time,” said Dr. Jennifer Goldman, a pediatrician at Children’s Mercy hospital in Kansas City, Missouri, who co-led the study.
Younger kids were more likely to have virus detected
Goldman and her colleagues analyzed nasal swabs and symptom reports from more than 800 students and staff in a large school district in Kansas City from November 2022 to May 2023.
They found that overall, more than 85 percent of all participants had at least one respiratory virus detected during that time and more than 80 percent had an episode of acute respiratory illness — though not necessarily at the same time.
More telling, 92 percent of pre-K and elementary school kids had a virus detected, compared with about 86 percent of middle school students, about 77 percent of high school students and 76 percent of staff.
The pre-K kids, ages 3 to 5, had the highest rates of actual illness, too, the study found.
Most of the viruses were the kinds that cause the common cold, including rhinovirus, which was found in 65 percent of participants, and types of seasonal coronavirus detected in about 30 percent. The virus that causes COVID-19 was found in about 15 percent of those studied.
Study confirms the experiences of pediatricians who are parents
The new study provides a baseline look at the burden of viruses in school settings, Goldman said.
It also confirms the real-world experience of pediatricians who are parents, like Dr. Nicole Torres of the University of Miami Health System.
“I can say this for my own children, who are now in their teens: They were sicker when they were younger,” she said.
The study also squares with older research that found that young kids play a key role in spreading respiratory viruses at home. Dr. Carrie Byington was co-author of a University of Utah study, published in 2015, that recruited 26 households to take nasal samples from everyone living in a home, every week, for a year.
That study found that children younger than 5 had virus detected for half of the weeks of the year, recalled Byington, who is now with the University of California, San Diego.
“And if you live in a household with multiple children, that proportion just goes higher, so it can appear as if someone is always sick,” she said.
How to prevent illness — or at least try to
Preventing illness in children at school or at home can be tough, experts acknowledge.
Being up to date on vaccinations for COVID-19 and influenza is important, they said. So is frequent handwashing, learning to cover coughs and keeping hands away from the eyes, nose and mouth. Cleaning and sanitizing frequently touched surfaces and objects and optimizing fresh air are also key.
When little ones do get sick, the best treatment is often supportive care like extra fluids and rest. In serious cases, medical providers may recommend medications to reduce fever or antiviral drugs.
It can take a couple weeks, however, for lingering symptoms like coughs to completely resolve. By then, the child may well have another cold.
“I do tell parents of younger children to expect them to be ill once every month, every month and a half,” Torres said. “It’ll seem that way.”


Russia holds scheduled nuclear drills, week after NATO

Russia holds scheduled nuclear drills, week after NATO
Updated 22 October 2025

Russia holds scheduled nuclear drills, week after NATO

Russia holds scheduled nuclear drills, week after NATO
  • The Russian maneuvers come with efforts faltering to solve the Ukraine war
  • Russia’s drill involved a mock intercontinental ballistic missile launch from a submarine in the Barents Sea

MOSCOW: Russia held planned strategic nuclear drills on Wednesday, a week after NATO began similar annual exercises, as tensions in Europe over the Ukraine war run high.
“Today we are conducting planned, I would like to emphasize, planned, nuclear forces training,” Russian President Vladimir Putin told generals in a televised meeting.
NATO began similar annual nuclear exercises focused on the North Sea region last Monday.


The Russian maneuvers come with efforts faltering to solve the Ukraine war, and after US President Donald Trump on Tuesday shelved planned peace talks with Putin.
Russia’s drill involved a mock intercontinental ballistic missile launch from a submarine in the Barents Sea, next to the Western bloc’s borders.
Another mock rocket was launched from a cosmodrome in northern Russia, while strategic bombers carried out air missile strikes, the Russian military said.
Videos released by the Russian Ministry of Defense showed the launches from ground, sea and aerial carriers.
Russia’s recent air incursions in Poland and Estonia, and a string of unexplained drone flights, have rattled NATO members and renewed calls to beef up the alliance’s defense.
Ukrainian President Volodymyr Zelensky failed to secure US long-range Tomahawk missiles on his last visit to Washington, despite weeks of calling for them.
Moscow has repeatedly criticized potential supplies of the nuclear-capable missiles, promising a serious escalation if they were to become reality.